Engenharia de Bioprocessos

In the end of this curricular unit the student will have acquired knowledge, skills and competencies that will enable:

- Understanding the different phases in bioprocess development and the particular challenges therein.

- Understanding the basic principles of metabolic engineering for the improvement of microbial strains/cellular lines.

- To be able to design genetic modifications to increase productivity/yield

- To be able to design, develop or optimize high cell density bioreactors

- To be able to scale-up or scale-down a bioreactor based on kinetic and transport data from the original scale

- To understand the specificities of animal cell bioprocesses for the production of biotherapeutics and for cell therapies in the health sector.