Princípios de Toxicologia

- basic knowledge on pharmacokinetics, pharmacodynamics, metabolism and toxicology as well as the biological and chemical mechanisms of these phenomena.

- understand the toxic biological effects due to exposure to environmental xenobiotics, food xenobiotics or pharmacological agents.

- understand the toxicological consequences associated with inter-individual variations in biotransformation enzymes, genetic polymorphisms and genetic variation in drug metabolism .

- knowledge of practical examples of the application of these concepts in the clinics, research and industry

- skills concerning analytical methodologies applied in pharmacology and toxicology studies

- knowledge on the national, European and worldwide regulations, their differences, similarities and implications.