Bioorgânica Estrutural

Advanced formation in the area of structural analysis of organic compounds with resource to nuclear magnetic resonance and X-ray Crystalography. This course has a special emphasis to the application of modern NMR techniques as well as monocrystal X-ray cristyalography techniques for structural elucidation and for the study of intermolecular interactions in a biological context.

At the end of the course the student should be able to: (1) acquire, process and interpret multidimensional NMR spectra as well as X-ray data. (2) plan strategies to the elucidation of complex structural problems, including the determination and validation of structures, conformational analysis and intermolecular interaction studies ("drug screening") (3) integrate and combine NMR and X-ray data with the courses of Organic Chemistry and Computational Chemistry (4) learn to use several computational on line tools as well as programs for molecular visualization and representation.

These skills will be explored in a context of original applications in a research environment.