Bioquímica Farmacêutica

Understand basic concepts in pharmacology. Criteria for ADME (Absorption; Distribution; Metabolism; Elimination) of a drug. To know drug biotransformation systems (Phase I and Phase II). To establish redox mediated processes by cytochromes P450 (CYPs) and its relationship with the structure of the enzyme. Familiarization with computational methods and Nuclear Magnetic Resonance for the analysis of drug/receptor interactions and in drug design. To evaluate the importance of inhibition/induction processes in CYP in drug- drug interactions.